Table S3 shows the Pallelic and Pempirical values for T2D of all SNPs, the latter generated by 10,000 permutations under the best model of genetic models for multiple test correction. Six of these SNPs showed nominal associations with 4 SNPs (rs1583645, rs6841638, rs10021007 and rs17046561) in CPE, 1 SNP (rs6583813) in IDE and 1 SNP (rs8117664) in PCSK2 with odds ratio (OR) and 95% confidence intervals (CI) ranging from 1.24 (1.01–1.51) to 1.34 (1.02–1.75)(Pempirical = 0.01–0.05). The gene discussed is PCSK2; the disease is type 2 diabetes mellitus.