WEE1 and parasitic infectious disease: There is a lack of validated drug discovery targets and lead compounds for HAT and other neglected diseases.12 Protein kinases have been explored as possible targets for HAT, as they play important roles in virtually every cellular event from cell division to stress response.13 Kinases are druggable targets, and crystal structures have been published for many of them.14 Bioinformatics searches of the T. brucei genome identified 176 parasite protein kinases,15, 16 making this family an attractive source of novel drug discovery targets for the treatment of HAT and other parasitic diseases.17–19