GNAL and Dystonia: More importantly, not all pathogenic mutations causing dystonia have been assigned to a DYT locus (e.g. mutations in SPR, CIZ1 or GNAL), whereas some syndromes with prominent dystonic components have been assigned to loci belonging to other movement disorders (e.g. PARK13 and PARK14) or vice versa (DYT3 and DYT12).