Ouyang et al., have developed a duplex qPCR assay for the detection of PCa, based on the quantification of alpha-methylacyl-CoA racemase (AMACR) and PCA3 in urine sediments, while Talesa et al. analyzed PSMA, Hepsin (HPN), PCA3, UDP-n-acetyl-alpha-d-galactosamine: polypeptide N-acetylgalactosaminyltransferase 3 (GalNAC-T3) and PSA using qPCR and concluded that the best combination of biomarkers for predictors of PCa included urinary PSA and PSMA [117]. This evidence concerns the gene KLK3 and posterior cortical atrophy.