CD4 and obesity due to melanocortin 4 receptor deficiency: In the ≥ 40 y group, male sex, overweight and obesity were also associated with subclinical atherosclerosis; however, factors related to HIV and HAART (CD4 above 350 cells/mL and use of NNRTI for at least 5 years) were also associated with subclinical atherosclerosis in this age group.