CYBB and diabetes mellitus: We have recently shown that in patients with diabetes mellitus, aspirin shifts arachidonic acid to nonenzymatic oxidation8 via NOX2 activation, an effect that ultimately leads to platelet 8‐iso‐PGF2α overexpression.8 In the present study we found that after aspirin intake, 8‐iso‐PGF2α overexpression was detected not only in platelets but also in urine and serum.