Moreover, we observed no stepwise increase in the prevalence of ALDH1A1 expression with TNM stage, lymph node involvement, ER, PR, and HER2 expression and triple negativity features of invasive ductal carcinoma tissue, it demonstrated that no significantly different expression of ALDH1 across these subtypes in invasive ductal carcinoma (Table 1). The gene discussed is ESR1; the disease is invasive ductal breast carcinoma.