Earlier studies have reported increased ALDH1A1 expression in 30% of breast tumor specimens and 34% of inflammatory breast carcinomas [13,15], while a recent report showed the presence of epithelial ALDH1 and expanded stromal ALDH1-positive cells in 43% and 69% of breast tumor biopsies, respectively [30]. This evidence concerns the gene ALDH1A1 and breast neoplasm.