ALDH1A1 and lung cancer: While elevated ALDH1A1 expression in tumor cells is reported to correlate with advanced tumor grade and stage in bladder and lung cancer, and patients with the ALDH1 phenotype in tumors display higher recurrence and shorter survival rates [28], tumor cell ALDH1 expression is significantly correlated specifically with triple negativity features or HER2 tumor types in the adjuvant series and tumor grade in the neoadjuvant cohort, and no significant enrichment for ALDH1 positive cells has been observed in postneoadjuvant therapy specimens, compared to pretreatment samples [30,31].