LMNA encodes the protein lamin A/C which forms part of the nuclear lamina, and mutations have been linked to many other disorders such as Charcot-Marie-Tooth neuropathy, progeria syndromes, restrictive dermopathy, limb-girdle muscular dystrophy, and mandibulo-acral dysplasia [126]. Here, LMNA is linked to limb-girdle muscular dystrophy.