Our results are consistent with a previous report that demonstrated a significant positive correlation between plasma levels of TBARS and sICAM-1 in patients with type 1 diabetes mellitus [52] and that hyperglycemia-induced oxidative stress induces an increase of circulating ICAM-1 levels [53] and the expression of RAGE in human endothelial cells [54]. The gene discussed is ICAM1; the disease is type 1 diabetes mellitus.