In the IL-10 null mice in the germ-free environment, the baseline values without carrageenan of KC (P < 0.05) (Figure 7(a)), fecal calprotectin (P < 0.05) (Figure 7(b)), Bcl10 (P < 0.001) (Figure 7(c)), and RelA (P < 0.05) (Figure 7(d)) were all significantly greater than in the C57BL/6 mice. This evidence concerns the gene IL10 and keratoconus.