Secretion of chemokines/cytokines from the neoplasm or inflammatory tissues such as vascular endothelial growth factor (VEGF), transforming growth factors (TGFs), fibroblast growth factors (FGF), platelet-derived growth factors (PDGF) and interleukin-8 (IL-8) is known to promote the migration of MSCs from the bone marrow [21,22]. Here, VEGFA is linked to neoplasm.