GPT and autoimmune hepatitis: In the AIH mouse model, the serum levels of ALT in mouse were elevated significantly after ConA injection for 20 h (n = 6, p < 0.01) (Figure 1A), and livers from ConA-induced hepatitis mice exhibited inflammatory cell infiltration, congestion and dilatation of blood vessel, as well as widespread hepatocellular necrosis in liver lobules (Figure 1B/C).