NUP214 and neoplasm: Through upregulating, the expression of CaN, NFATC2, NFATC2ip, and NFATC3, CA is able to improve the transcription of immune factors like IL-2R and IFN-γ, stimulate proliferation and activation of T cells, NK cells, and macrophage, strengthen monitoring and killing abilities of cancer cells, and inhibit growth of tumor finally.