Evaluation for EDS IV, EDS VI, and Marfan and Loeys-Dietz syndrome involved sequencing and deletion/duplication analysis of the COL3A1, TGFβR1, TGFβR2,  and  FBN1 genes as well as deoxypyridinoline/pyridinoline ratio in the urine, all of which were normal. Here, COL3A1 is linked to Ehlers-Danlos syndrome, vascular type.