These Tg mice show suppressed growth of Lewis lung carcinoma (LLC) cell and B16 melanoma cell-transplants, indicating CXCL14/BRAK, first found as a tumor progression suppressor for HNSCC, also suppresses the progression of tumors of other tissue origins by a paracrine or endocrine mechanism [6]. The gene discussed is CXCL14; the disease is head and neck squamous cell carcinoma.