A targeted peptide vaccine against EGFRvIII, a mutated form of the EGFR, entered a phase I clinical trial, the Vaccine for Intra-Cranial Tumors I (VICTORI), and has continued to the phase II study, A Complementary Trial of an Immunotherapy Against Tumor Specific EGFRvIII (ACTIVATE) [145]. The gene discussed is EGFR; the disease is neoplasm.