Zhang et al [27] showed that a 5-day infusion of Ang-(1–7) reduced proteinuria and improved glomerulosclerosis in a rat model of thy-1 induced glomerulonephritis, whereas van der Wouden et al reported that infusion of Ang-(1–7) was not able to reduce proteinuria in ADR-induced nephropathy [26]. This evidence concerns the gene THY1 and glomerulonephritis.