PCT increases predicted bloodstream invasion, septic shock and organ failure and carried greater prognostic significance in the course of infectious disease than CRP [on D7] thus supporting that PCT is more useful in predicting infectious complications, also in the ICU, even when not predicting new BSI [2], [4]–[6], [8]–[10], [12], 14,20,24–27,30,31. This evidence concerns the gene CRP and Shock.