YAP1 and neoplasm: Cox’s proportional hazards model, adjusted for gender, age, tumor size, tumor location, differentiation status, and TNM stage, compared with YAP or TAZ expression, showed that negative expression of both YAP and TAZ were associated with significantly improved overall survival; whereas, expression of both YAP and TAZ were associated with significantly poor overall survival (Table 3), with the adjusted HR being 3.118 (95% CI: 1.017–9.559; P<0.001).