Consistent with a previous report, we found a shared and distinct relationship between YAP and TAZ function [29]: Compared to TAZ, YAP had a more significant effect on the proliferation and apoptosis of CRC cells; in contrast, the converse situation was observed for migration and invasion; as expected, all of these effects were most suppressed when both YAP and TAZ were knocked down. This evidence concerns the gene YAP1 and colorectal carcinoma.