Our results were consistent with a previous study [7], in that the expression levels of both YAP and TAZ were significantly elevated in the majority of CRC tissues compared to adjacent normal tissues; however, in contrast to reports on breast cancer and lung squamous cell carcinoma, we found no discrepancy between cytoplasmic and nuclear expression of YAP or TAZ in CRC tissues [15]. This evidence concerns the gene YAP1 and breast cancer.