TP53 and neoplasm: The p53 tumour-suppressor gene is expressed ubiquitously in all cell types as an inactive, latent transcription factor that becomes active only when the cells are subjected to a variety of cellular insults such as DNA damage, radiation, hypoxia, telomere erosion, nutrient deprivation, transcription inhibition, depletion of nucleotide pools, oncogene expression, heat shock, or oxidative stress (OS), among others [1]–[6].