Additional analyses of coibamide A-induced autophagy, relative to starvation-induced autophagy, in human SF-295 (Fig. S2)) and U251 (Fig. S3) glioblastoma cells also revealed increases in endogenous LC3-II expression with no change in the phosphorylation state of p70 S6K1 (Thr-389) or the mobility of 4EBP-1. The gene discussed is EIF4EBP1; the disease is glioblastoma.