However, we detected neither a striking difference in Klf4 at transcriptional and translational levels upon exogenous expression of SATB1, nor any SATB1 binding on the Klf4 locus using a ChIP assay, which could be caused by a possible genomic structure change within the Klf4 locus in the F9 cell, a carcinoma cell line (Figure S5E). This evidence concerns the gene KLF4 and carcinoma.