Ex vivo evaluation of the radiotracer biodistribution demonstrated significantly greater %ID/g in tumors infected with Ad-CMV-HA-SSTR2 by both the IA and IT routes as compared to tumors infected with control Ad-CMV-GFP virus (p<0.01 for IA, n = 6; and p<0.02 for IT, n = 6; Fig. 2A) and there was no difference in expression by tumor directed IA or IT routes of Ad-CMV-HA-SSTR2 delivery. Here, SSTR2 is linked to neoplasm.