IKBKB and asthma: Various therapy strategies targeted at the NF-κB signaling pathway such as p65-specific antisense and small interfering ribonucleic acid [10, 22], NF-κB-specific decoy oligonucleotide [23], IKKβ-selective small molecule inhibitors [24], and proteasome inhibitors [25] have demonstrated beneficial effects in experimental asthma models.