Early administration of high-dose BHT (CLP + BHT-H6) significantly reduced elevations of IL-6 and IL-10 as compared with the sepsis-control group at 12 hrs postoperatively (bP < 0.05, IL-6: 868.24 versus 3177.64 pg/mL; IL-10: 85.35 versus 229.45 pg/mL). Here, IL6 is linked to Sepsis.