DROSHA and Huntington disease: Striatal miR-22, miR-29c, miR-128, miR-132, miR-138, miR-218, miR-222, miR-344, and miR-674-3p, as well as the cellular levels of Drosha were shown to be downregulated in both YAC128 and R6/2 transgenic mouse models of Huntington's disease (HD) [55].