MYD88 and Splenomegaly: Myd88/Trif-null mice exhibited similar changes of their phenotypic composition in the LIN− compartment as wild type controls during acute malaria (Figure S4A) accompanied by splenomegaly comparable to wild type controls (spleen weight controls uninfected: 47.8±12.4 mg, controls day 7 after infection: 234±63.2 mg; Myd88/Trif-null uninfected 38.1±19.7 mg, Myd88/Trif-null day 7 after infection: 207.2±89.1 mg).