LAMP-1 was also more rapidly associated with autophagosomes harboring 188NADase- compared to parent strain 188, although less so than the SLO-mutant: 27% of autophagosomes containing 188NADase- were positive for LAMP-1 at 1 h post-infection, 64% at 3 h, and 82% at 6 h (Figure 5A,B). The gene discussed is LAMP1; the disease is infection.