ADAM9 and non-small cell lung carcinoma: By contrast, for the sub-group of ADAM9-low stage I NSCLC, with low expression of ADAM9, demonstrating a significantly longer survival time, the 5-year survival rate was 88.9% in our study, suggesting that no further adjuvant chemotherapy is necessary for this group of stage I NSCLC, especially considering long-term chemotherapy-associated toxicity (22,23).