Follicular lymphoma B cells were additionally found to respond to APRIL-TACI stimulation by phosphorylating p85 PI3K, Akt, mTOR, 4E-BP1, and p70S6K, and PI3K inhibitors blocked these APRIL-induced activities and cellular proliferation (Gupta et al., 2009). Here, TNFSF13 is linked to follicular lymphoma.