PDLIM7 and Epstein-Barr virus infection: The lack of detectable BNLF amplification in 4 cases of IHC-positive staining in the HLEAFab group and 5 cases in the S12 group, as well as BNLF amplification in 3 cases of negative staining in the HLEAFab group and 3 cases in the S12 group, indicates that LMP1 expression is not required for the maintenance or regulation of latent EBV infection in epithelial cells and thus BNLF1 fragments may be lost following EBV-induced cell transformation in the cell differentiation and proliferation process.