In their recent article, published in Frontiers in Neurology, Mullen et al. (2012) demonstrated that anti-phosphatidylserine/prothrombin (PS/PT) antibodies are independently associated with stroke or death in non-antiphospholipid syndrome (APS) patients with transient ischemic attacks (TIA). The gene discussed is F2; the disease is autoimmune polyendocrinopathy.