Indeed, we identify a minimal overlap of four different network genes with the breast cancer signatures of Wang et al. (2005) (HDAC1, PIAS3) and van’t Veer et al. (2002) (DUSP4, DVL3) and a maximal overlap of 11 network genes with the ovarian cancer specific gene signature of Mok et al. (2009) (MAPK9, ARAF, PEPB1, MAPK1, TGFB3, ERBB2, ADAM12, GREM1, SMAD2, JAG2, GLI3). This evidence concerns the gene SMAD2 and ovarian cancer.