In addition to recruitment of adaptor proteins, activated RTKs present a binding and activating interface for several other cancer relevant signaling cascades including PLCG, SRC, and STAT (Noh et al., 1995; Kamat and Carpenter, 1997; Ishizawar and Parsons, 2004; Yu et al., 2009). The gene discussed is SOAT1; the disease is cancer.