Indeed, we identify a minimal overlap of four different network genes with the breast cancer signatures of Wang et al. (2005) (HDAC1, PIAS3) and van’t Veer et al. (2002) (DUSP4, DVL3) and a maximal overlap of 11 network genes with the ovarian cancer specific gene signature of Mok et al. (2009) (MAPK9, ARAF, PEPB1, MAPK1, TGFB3, ERBB2, ADAM12, GREM1, SMAD2, JAG2, GLI3). The gene discussed is GREM1; the disease is breast carcinoma.