Cheng et al. [13] reported that Lunx mRNA was the most specific biomarker with the highest sensitivity when compared with CK19, CEA, vascular endothelial growth factor-C (VEGF-C), and heterogeneous ribonuclear protein (hnRNP) for the differential diagnosis of non-small cell lung cancer from pleural effusion. The gene discussed is VEGFC; the disease is Pleural effusion.