PTK6 expression was significantly associated with tumor size (T classification) (P<0.001, Table 2), clinical stage (P<0.001, Table 2), and metastasis (P=0.016, Table 2) in those all NPC patients; however, there was no significant correlation between PTK6 expression and other clinicopathological features, such as patient age, sex, lymphoid nodal states (N classification), local-regional relapse, and WHO classification (P>0.05, Table 2). This evidence concerns the gene PTK6 and nasopharyngeal carcinoma.