BCAT1 and nasopharyngeal carcinoma: Cytoplastic immunostaining signals of BCAT1 could be detected at different stages, but the positive rates differed greatly, which were 23.6% (17/72), 75.0% (18/24), 88.9% (8/9) and 88.8% (71/80) in normal epithelia, low-to-moderate grade atypical hyperplasia tissues, high-grade atypical hyperplasia tissues and NPC tissues, respectively (Figure 1, Table 1, P < 0.05), indicating that up-regulation of BCAT1 is an early event in NPC pathogenesis.