After classifying these N1 patients into three groups based on the expression of CK19 in primary liver tumor, we found that patients with CK19(+) LNM and CK19(+) primary tumor had a significantly poorer OS than patients with CK19(−) LNM and CK19(−) primary tumor (P = 0.042) (Figure 3). This evidence concerns the gene KRT19 and liver cancer.