On the other hand, patient age, gender, cigarette smoking, alcohol consumption, hepatitis viral status, preoperative total bilirubin, preoperative AFP, preoperative alkaline phosphatase (ALK-P), Child-Pugh classification, tumor size, T stage, tumor rupture, vascular invasion, daughter nodules, and histologic grade were not related to CK19 expression in primary liver tumor. This evidence concerns the gene AFP and Hepatitis.