Although there was relatively high CDC20 expression in normal colon epithelial CCD841-coN cells, most likely due to individual differences, the IHC analysis confirmed the elevated expression of CDC20 protein in the 126 CRC tissues compared with matched, adjacent non-tumor tissues (Figure 1B, P < 0.001, Wilcoxon signed rank test, n =126). The gene discussed is CDC20; the disease is neoplasm.