Using the full set of 11 procedures, the automated method ranked these as ALS-causing genes in the following order: SOD1, TARDBP, FUS, ANG, SPG11, NEFH, OPTN, ALS2, SETX, FIG4, VAPB, DCTN1, TAF15, VCP, DAO. The gene discussed is ALS2; the disease is amyotrophic lateral sclerosis.