GSDMB and asthma: The SNP rs2305480, a missense SNP in the gene GSDMB, was not reported in the previous GWAS study (Moffatt et al., 2007) but has been reported as an asthma-associated SNP in a later larger scale study by the GABRIEL consortium (including the MAGIC data, Moffatt et al., 2010) and was found to be strongly interacting with exposure to tobacco smoke in early life (Bouzigon et al., 2008).