IL10 and systemic lupus erythematosus: IL-10-deficiency also aggravates autoimmune pathology in a range of experimental models including rheumatoid arthritis (RA) (Hata et al., 2004), experimental autoimmune neuritis (Bai et al., 1997), systemic lupus erythematosus (SLE) (Beebe et al., 2002), and experimental autoimmune encephalomyelitis (EAE) (Bettelli et al., 1998).