IL10 and infection: A dysregulated TH1 response and subsequent tissue damage are also observed in IL-10-deficient mice following infection with other pathogens, including Leishmania major (Anderson et al., 2007), Trypanosoma cruzi (Abrahamsohn and Coffman, 1996; Hunter et al., 1997), Plasmodium chabaudi (Linke et al., 1996), Listeria monocytogenes (Deckert et al., 2001), murine cytomegalovirus (Oakley et al., 2008), and respiratory influenza virus (Sun et al., 2009).