NR3C2 and chronic obstructive pulmonary disease: On multivariate analysis (Table 4) with ER as the dependent variable and age, presence of COPD, mineralocorticoid receptor antagonist use, heart rate, PR interval, QRS interval, and dialysis as covariates, only the QRS duration remained a significant independent predictor of ER (OR 0.97, 95% CI, 0.94–0.99, p = 0.01).