These three groups with different expression levels of YKL-40 were found to be significantly correlated with different degrees of vascularization with CD34-positive vessels in tumor sections (p = 0.006), in which the blood vessel density of the two groups that demonstrated high and medium levels of YKL-40 were 2.1 and 1.6-fold greater than the group expressing low YKL-40, respectively. The gene discussed is CHI3L1; the disease is neoplasm.