We also did not evaluate other risk factors such as serum adiponectin, CRP, homocysteine and arterial intima-media thickness.26,27 However, it is very encouraging to see the decreasing trend in the prevalence of the cardiovascular risk factors in our children with CAH most likely attributed to significant reduction in hydrocortisone and fludrocortisone doses over the last decade. This evidence concerns the gene CRP and congenital adrenal hyperplasia.