[6] Considerable effort has, thus, focused on identifying noninvasive tools to aid in the diagnosis of lymphoma. These include molecular analysis of gene rearrangements, immunohistochemistry/flow cytometry analysis of cell surface markers, and quantification of intraocular cytokines. Interleukin (IL)-10, a cytokine of interest, is selectively expressed in malignancy and has been shown to function in stimulating B-cell antibody production [7] and evading cellular immunity. [8] Alternatively, IL-6 is elevated in the setting of inflammation unrelated to malignancy. [9]. This evidence concerns the gene IL6 and lymphoma.