Vargova et al. recently reported that overexpression of v-myb myeloblastosis viral oncogene homolog (MYB) associates with and activates the transcription of the miR-155 promoter in a subset of CLL patients; however, the correlation between MYB and miR-155 expression levels was not strong [19]. Here, MYB is linked to B-cell chronic lymphocytic leukemia.