Human neuroblastoma SH-SY5Y cells with stable overexpression of wild type APP (SH-SY5Y-APP695wt) were transfected with either anti-LRRTM3 siRNA (si-LRRTM3, SASI_Hs01_00163676, Sigma) or control (si-control, SIC001 MISSION Universal Negative Control#1, Sigma). The gene discussed is APP; the disease is neuroblastoma.