This phenomenon has also been frequently noted in anecdotal reports and empirical studies of ovarian cancer survivors, with the CA125 biomarker coming to play a prominent role in many women's experiences of cancer survivorship (for example, Hamilton, 1999; Guppy and Rustin, 2002; Howell et al, 2003; Palmer et al, 2006; Parker et al, 2006; Chitale, 2009). This evidence concerns the gene MUC16 and ovarian cancer.