However, clear dimerization of EGFR (at ~360 kDa immunoreactive bands) was also evident in the four different tumor cells, and in cells exposed to hEGF (100 ng/ml) treatment; such dimerization gradually increased with the dose of gefitinib at 0.01, 0.05, 0.1, 0.5, 1, 5, and 10 μM (final concentration). Here, EGFR is linked to neoplasm.