EGFR and colorectal cancer: Recent studies have seen rapid evolution of drug resistance in cancers which occur due to mutations in the epidermal growth factor receptors (EGFR), including non-small-cell lung cancer (NSCLC) and colorectal cancers (Kobayashi et al. 2005; Turke et al. 2010; Sequist et al. 2011; Diaz et al. 2012).